GH Axis
CJC-1295 (No DAC)
Modified GRF (1-29) · Mod GRF 1-29
Tetra-substituted GHRH(1-29) analogue for pulsatile GH-release research.
2 mg5 mg10 mg
CJC-1295 (With DAC)
Also known as: CJC-1295 DAC · Drug Affinity Complex GRF
Growth Hormone Axis In stock Box of 10 vials 1 reference
Long-acting GHRH analogue: one dose, days of elevated GH and IGF-1.
Available sizes
| SKU | Per vial | Pack | |
|---|---|---|---|
| CD2 | 2 mg | 10 vials / box | |
| CD5 | 5 mg | 10 vials / box | |
| CD10 | 10 mg | 10 vials / box |
Order CJC-1295 (With DAC)
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CJC-1295 with DAC adds a maleimidoproprionic-acid linker (the Drug Affinity Complex) to the tetra-substituted GRF(1-29) backbone. The linker covalently binds circulating albumin, extending the half-life from minutes to roughly six to eight days.
In healthy adults, single CJC-1295 doses increased plasma GH 2- to 10-fold for six days or more and IGF-1 1.5- to 3-fold for 9 to 11 days; repeated weekly or bi-weekly dosing maintained the elevation with an estimated half-life of 5.8–8.1 days 1.
At a glance
- Albumin-binding DAC linker; ~6–8 day half-life
- Published PK/PD in J Clin Endocrinol Metab
- 2, 5 and 10 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
- Form
- Lyophilized powder
- Purity
- HPLC-verified — Certificate of Analysis available on request
- Pack size
- Box of 10 vials
- Storage
- Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
- Formula
- C165H269N47O46
- Mol. weight
- 3647.3 g/mol
- CAS No.
- 863288-34-0
Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.
- Teichman SL, Neale A, Lawrence B, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2005;91(3):799-805.
Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.
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